Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ACE | P12821 | 5/20 | 0.61 |
| ▸ | MME | P08473 | 4/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.58 |
| ▸ | FPR2 | P25090 | 5/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180354 | 1.00 | NPSR1 (0.69) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL5180357 | 1.00 | NPSR1 (0.69) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL2099396 | 0.88 | NPSR1 (0.56) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL2099399 | 0.88 | NPSR1 (0.56) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL11459400 | 0.87 | ACE (0.63) | NPSR1ACEMMEACE2NAALAD2 | |
| SCHEMBL11459401 | 0.87 | ACE (0.63) | NPSR1ACEMMEACE2NAALAD2 | |
| SCHEMBL8726475 | 0.87 | ACE (0.63) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL908204 | 0.87 | ACE (0.63) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL908205 | 0.87 | ACE (0.63) | NPSR1ACEMMEACE2FPR2 | |
| SCHEMBL8842603 | 0.87 | GPR34 (0.66) | NPSR1ACEMMEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808049-A | ANTITUMOR | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5585512-A | ANTICARCINOGENIC AGENT RESISTANT HAVING BLOCKING AGENT RESISTANT TO HYDROLYSIS IN BLOOD | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1996-12-17 | — | — | US | disclosed |