Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.45 |
| ▸ | FNTB | P49356 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8613841 | 1.00 | MEN1 (0.47) | MEN1KMT2AFNTAFNTBRAB9A | |
| SCHEMBL7837437 | 0.95 | KMT2A (0.51) | MEN1KMT2AFNTAFNTBRAB9A | |
| SCHEMBL7837444 | 0.95 | KMT2A (0.51) | MEN1KMT2AFNTAFNTBRAB9A | |
| SCHEMBL7848067 | 0.84 | KMT2A (0.60) | KMT2AFNTAFNTBRAB9A | |
| SCHEMBL8790433 | 0.84 | KMT2A (0.60) | KMT2AFNTAFNTBRAB9A | |
| SCHEMBL9828951 | 0.76 | FNTA (0.62) | MEN1KMT2AFNTAFNTBALDH1A1 | |
| SCHEMBL2324069 | 0.76 | FNTA (0.62) | MEN1KMT2AFNTAFNTBALDH1A1 | |
| SCHEMBL13018869 | 0.76 | RAB9A (0.43) | MEN1KMT2ARAB9AITGB1ITGA4 | |
| SCHEMBL7335664 | 0.75 | RAB9A (0.52) | RAB9AITGB1ITGA4ALDH1A1CCR1 | |
| SCHEMBL27974453 | 0.75 | FNTA (0.49) | MEN1KMT2AFNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837857-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0837857-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996031525-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-10 | — | — | WO | disclosed |