Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848067 | 1.00 | KMT2A (0.60) | KMT2AAPOBEC3GL3MBTL1CNR1CNR2 | |
| SCHEMBL7837437 | 0.89 | KMT2A (0.51) | KMT2AFNTAFNTBUSP2RAB9A | |
| SCHEMBL7837444 | 0.89 | KMT2A (0.51) | KMT2AFNTAFNTBUSP2RAB9A | |
| Trifluoroacetic Acid SCHEMBL8613841 | 0.84 | MEN1 (0.47) | KMT2AFNTAFNTBRAB9A | |
| Trifluoroacetic Acid SCHEMBL8613845 | 0.84 | MEN1 (0.47) | KMT2AFNTAFNTBRAB9A | |
| SCHEMBL24898028 | 0.76 | RAB9A (0.55) | KMT2ACNR2RAB9A | |
| SCHEMBL13018869 | 0.76 | RAB9A (0.43) | KMT2ACNR2RAB9A | |
| SCHEMBL2323686 | 0.76 | L3MBTL1 (0.74) | KMT2AAPOBEC3GL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL18095164 | 0.76 | L3MBTL1 (0.74) | KMT2AAPOBEC3GL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL7837441 | 0.74 | CNR2 (0.39) | KMT2AAPOBEC3GCNR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755383-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0755383-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-01-29 | — | — | EP | disclosed |