Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613882 | 0.84 | MAOA (0.67) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8612202 | 0.84 | MAOA (0.67) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8614361 | 0.84 | MAOA (0.67) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8610424 | 0.83 | MAOA (0.65) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8610696 | 0.82 | CHRM2 (0.71) | CHRM2L3MBTL1SCN8ALMNA | |
| SCHEMBL8610456 | 0.80 | SLC2A1 (0.45) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7367054 | 0.79 | HPGD (0.51) | LMNACYP2D6 | |
| SCHEMBL8328363 | 0.78 | CHRM2 (0.79) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10045185 | 0.77 | CHRM2 (0.92) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8019471 | 0.77 | CHRM2 (0.82) | CHRM2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |