Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613882 | 1.00 | MAOA (0.67) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8614361 | 1.00 | MAOA (0.67) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL8610424 | 0.98 | MAOA (0.65) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL7628857 | 0.88 | MEN1 (0.63) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8610214 | 0.85 | SIGMAR1 (0.64) | SIGMAR1 | |
| SCHEMBL8610149 | 0.84 | MAOA (0.62) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8613857 | 0.84 | CHRM2 (0.67) | MAOACHRM2HDAC3HDAC1HDAC2 | |
| SCHEMBL8614791 | 0.82 | MAOA (0.59) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8851048 | 0.82 | MAOA (1.00) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL4642587 | 0.82 | MAOA (1.00) | MAOACHRM2SIGMAR1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |