Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174880 | 0.78 | RAB9A (0.64) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL3374076 | 0.77 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL6311629 | 0.77 | MAPT (0.66) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1107420 | 0.76 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31578900 | 0.76 | GAA (0.55) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL8847597 | 0.76 | EGLN1 (0.58) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL15888379 | 0.76 | ADORA2A (0.46) | SMN1; SMN2GAAPOLBNPC1MAPT | |
| SCHEMBL1525238 | 0.75 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11012092 | 0.75 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8847537 | 0.75 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873304-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997019053-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |