Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847566 | 0.83 | KMT2A (0.54) | KMT2AMEN1LMNATP53HTT | |
| SCHEMBL8847537 | 0.83 | MEN1 (0.54) | KMT2AMEN1LMNATP53ALDH1A1 | |
| SCHEMBL3368044 | 0.82 | EGLN1 (0.69) | EGLN1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL31578900 | 0.81 | GAA (0.55) | KMT2AMEN1LMNATP53HTT | |
| SCHEMBL9823475 | 0.81 | RAB9A (0.54) | EGLN1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL6311629 | 0.77 | MAPT (0.66) | KMT2AMEN1LMNATP53ALDH1A1 | |
| SCHEMBL11632159 | 0.77 | MAPT (0.55) | KMT2AMEN1TP53ALDH1A1CYP2C9 | |
| SCHEMBL8613865 | 0.76 | MEN1 (0.56) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL31578699 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1LMNATP53HTT | |
| SCHEMBL8847666 | 0.76 | MAPT (0.53) | KMT2AMEN1LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620968-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5527792-A | CARBA- AND OXACEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| US-5525599-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1996-06-11 | — | — | US | disclosed |