Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400232 | 0.91 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4243129 | 0.91 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10599787 | 0.87 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL9683516 | 0.87 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL610755 | 0.87 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL28003430 | 0.87 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27693913 | 0.84 | ALDH1A1 (0.68) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL23169792 | 0.83 | KMT2A (0.55) | KMT2AHSD17B10MAPTALDH1A1KDM4E | |
| SCHEMBL14513468 | 0.83 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22826428 | 0.83 | KMT2A (0.58) | KMT2AMEN1HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836591-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-04-22 | — | — | EP | claimed |
| WO-1996040628-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | THE UNIVERSITY OF SASKATCHEWAN (CA) | 1996-12-19 | — | — | WO | claimed |
| EP-0836591-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-04-22 | — | — | EP | disclosed |
| WO-1996040628-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | THE UNIVERSITY OF SASKATCHEWAN (CA) | 1996-12-19 | — | — | WO | disclosed |