SCHEMBL8614029

SCHEMBL8614029

CCCc1ccc(C2=Cc3ccccc3[CH]2)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.36
CNR1 P21554 2/20 0.36
SLC22A12 Q96S37 4/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
CTSL P07711 1/20 0.30
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30
ELANE P08246 1/20 0.30
CTSG P08311 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615237 0.91 CNR2 (0.36) CNR2CNR1ELANECTSG
SCHEMBL216311 0.81 NR1H2 (0.33)
SCHEMBL30537733 0.76 KDM4E (0.46) CNR2CNR1SLC22A12KDM4EALDH1A1
SCHEMBL798769 0.76 KDM4E (0.46) CNR2CNR1SLC22A12KDM4EALDH1A1
SCHEMBL216178 0.76 KDM4E (0.31) KDM4EALDH1A1GAAHPGD
SCHEMBL11057507 0.72 ALDH1A1 (0.41) CNR2CNR1SLC22A12KDM4EALDH1A1
SCHEMBL2966272 0.71
SCHEMBL11050977 0.70 CNR2 (0.45) CNR2CNR1SLC22A12KDM4EALDH1A1
SCHEMBL219317 0.70 CYP2D6 (0.36) KDM4EALDH1A1HPGD
SCHEMBL2971433 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837865-A1 PROCESS FOR CONVERTING THE ACHIRAL MESO FORM OF AN ANSA-METALLOCENE COMPLEX INTO THE CHIRAL RACEMIC FORM BASF AKTIENGESELLSCHAFT (DE) 1998-04-29 EP disclosed
WO-1997003080-A1 PROCESS FOR CONVERTING THE ACHIRAL MESO FORM OF AN ANSA-METALLOCENE COMPLEX INTO THE CHIRAL RACEMIC FORM BASF AKTIENGESELLSCHAFT (DE) 1997-01-30 WO disclosed