Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | MOK | Q9UQ07 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615672 | 0.83 | MOK (0.38) | ACP1ACACAMOKPDE10AADORA1 | |
| SCHEMBL8619221 | 0.82 | DHODH (0.44) | ACP1ABCB1ABCC1ABCG2MOK | |
| SCHEMBL8613487 | 0.81 | KDM4E (0.44) | ACP1ABCB1ABCC1ABCG2TRPV1 | |
| SCHEMBL8620687 | 0.80 | PDE10A (0.45) | ACP1ACACAPDE10AADORA1CCR6 | |
| SCHEMBL8615997 | 0.80 | CCR6 (0.45) | ACP1ABCB1ABCC1ABCG2PDE10A | |
| SCHEMBL8613769 | 0.79 | ACP1 (0.39) | ACP1ABCB1ABCC1ABCG2MOK | |
| SCHEMBL8619903 | 0.79 | ACP1 (0.39) | ACP1ABCB1ABCC1ABCG2PDE10A | |
| SCHEMBL8616699 | 0.79 | ACP1 (0.39) | ACP1ABCB1ABCC1ABCG2PDE10A | |
| SCHEMBL8618767 | 0.79 | MAPT (0.40) | ACP1ABCB1ABCC1ABCG2MOK | |
| SCHEMBL8618998 | 0.78 | ABCB1 (0.47) | ACP1ABCB1ABCC1ABCG2MOK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |