Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615997 | 0.87 | CCR6 (0.45) | ACP1ABCB1ABCC1ABCG2CYP2C9 | |
| SCHEMBL8619903 | 0.86 | ACP1 (0.39) | ACP1ABCB1ABCC1ABCG2CYP2C9 | |
| SCHEMBL8613487 | 0.86 | KDM4E (0.44) | ACP1ABCB1ABCC1ABCG2NPC1 | |
| SCHEMBL8618767 | 0.86 | MAPT (0.40) | ACP1ABCB1ABCC1ABCG2NPC1 | |
| SCHEMBL8618998 | 0.84 | ABCB1 (0.47) | ACP1ABCB1ABCC1ABCG2PDE10A | |
| SCHEMBL8617718 | 0.84 | PDE10A (0.56) | ACP1ABCB1ABCC1ABCG2NPC1 | |
| SCHEMBL8617753 | 0.83 | ACP1 (0.51) | ACP1ABCB1ABCC1ABCG2SLC2A1 | |
| SCHEMBL8615310 | 0.83 | MEN1 (0.41) | ACP1ABCG2RAB9ATDP1MEN1 | |
| SCHEMBL8619728 | 0.83 | KEAP1 (0.43) | ACP1ABCB1ABCC1ABCG2KDM4E | |
| SCHEMBL8613362 | 0.82 | ACHE (0.41) | ACP1ACHEABCB1ABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |