SCHEMBL8614366

SCHEMBL8614366

CC(C)c1cc(OCCCC(=O)OCc2ccccc2)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccccc1)S2(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8614493 0.97 ELANE (0.42) ELANE
SCHEMBL7407088 0.95 ELANE (0.41) ELANE
SCHEMBL7448570 0.89 ELANE (0.42) ELANE
SCHEMBL8615682 0.88 ELANE (0.45) ELANE
SCHEMBL7404141 0.85 ELANE (0.43) ELANE
SCHEMBL8614058 0.84 ELANE (0.57) ELANE
SCHEMBL7452856 0.83 ELANE (0.49) ELANE
SCHEMBL7407090 0.82 CARM1 (0.35) ELANE
SCHEMBL7280450 0.77 ELANE (0.69) ELANE
SCHEMBL7448574 0.75 CARM1 (0.38) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 US disclosed