SCHEMBL8615682

SCHEMBL8615682

CC(C)c1cc(OCCCCCC(=O)O)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccccc1)S2(=O)=O

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8609837 0.97 ELANE (0.46) ELANE
SCHEMBL8614493 0.91 ELANE (0.42) ELANE
SCHEMBL7404141 0.91 ELANE (0.43) ELANE
SCHEMBL7399078 0.89 ELANE (0.46) ELANE
SCHEMBL7452856 0.85 ELANE (0.49) ELANE
SCHEMBL7448570 0.84 ELANE (0.42) ELANE
SCHEMBL7407088 0.84 ELANE (0.41) ELANE
SCHEMBL7410359 0.77 CASP3 (0.38)
SCHEMBL8609841 0.76 ELANE (0.60) ELANE
SCHEMBL8611482 0.74 ELANE (0.55) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 US disclosed