Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.38 |
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448570 | 0.86 | ELANE (0.42) | ELANE | |
| SCHEMBL7407090 | 0.85 | CARM1 (0.35) | CARM1ELANE | |
| SCHEMBL8615757 | 0.76 | ELANE (0.33) | ELANE | |
| SCHEMBL8614366 | 0.75 | ELANE (0.43) | ELANE | |
| SCHEMBL8614493 | 0.74 | ELANE (0.42) | ELANE | |
| SCHEMBL7407088 | 0.71 | ELANE (0.41) | ELANE | |
| SCHEMBL8615682 | 0.69 | ELANE (0.45) | ELANE | |
| SCHEMBL7408952 | 0.69 | ELANE (0.33) | ELANE | |
| SCHEMBL7404663 | 0.69 | ELANE (0.35) | ELANE | |
| SCHEMBL8614058 | 0.67 | ELANE (0.57) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010243-A1 | 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (US) | 1997-03-20 | — | — | WO | disclosed |