Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730199 | 0.89 | GPR119 (0.35) | OPRK1GPR119ALOX5APSMYD3 | |
| SCHEMBL14730311 | 0.86 | GPR119 (0.36) | OPRK1GPR119ALOX5AP | |
| SCHEMBL14730200 | 0.85 | OPRK1 (0.36) | OPRK1GPR119ALOX5APHRH4 | |
| SCHEMBL8614390 | 0.82 | GPR119 (0.38) | OPRK1GPR119ALOX5AP | |
| SCHEMBL6125573 | 0.82 | GPR119 (0.38) | GPR119ALOX5APHRH4 | |
| Hydrochloric Acid SCHEMBL6125721 | 0.81 | GPR119 (0.37) | GPR119ALOX5APHRH4 | |
| SCHEMBL14730201 | 0.79 | GPR119 (0.41) | OPRK1GPR119ALOX5AP | |
| SCHEMBL470597 | 0.77 | GPR119 (0.45) | GPR119ALOX5AP | |
| SCHEMBL14730328 | 0.76 | GPR119 (0.37) | OPRK1GPR119ALOX5APHRH4 | |
| SCHEMBL6125572 | 0.76 | GPR119 (0.41) | GPR119ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066077-A1 | 1,4 DI SUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |