Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.47 |
| ▸ | CD99 | P14209 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610847 | 1.00 | KDM4E (0.53) | KDM4EPKMADORA2AADORA3ADORA1 | |
| SCHEMBL8613545 | 0.89 | KDM4E (0.50) | KDM4EPKMADORA2AADORA3ADORA1 | |
| SCHEMBL8613540 | 0.89 | KDM4E (0.50) | KDM4EPKMADORA2AADORA3ADORA1 | |
| SCHEMBL8614745 | 0.86 | SLC29A1 (0.51) | KDM4EPKMADORA2AADORA3ADORA1 | |
| SCHEMBL8614735 | 0.86 | SLC29A1 (0.51) | KDM4EPKMADORA2AADORA3ADORA1 | |
| SCHEMBL8613394 | 0.84 | ADORA2A (0.67) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8613408 | 0.84 | ADORA2A (0.67) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8615046 | 0.83 | ADORA2A (0.55) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8615037 | 0.83 | ADORA2A (0.55) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8970966 | 0.82 | ADORA3 (0.60) | KDM4EPKMADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |