Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.52 |
| ▸ | RARA | P10276 | 12/20 | 0.52 |
| ▸ | RARG | P13631 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578640 | 0.92 | RARB (0.49) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL6574370 | 0.87 | RARB (0.67) | RARBRARARARGCYP3A4CYP26A1 | |
| SCHEMBL6578008 | 0.83 | RARB (0.51) | RARBRARARARGCYP3A4CYP26A1 | |
| SCHEMBL6578025 | 0.81 | RARB (0.65) | RARBRARARARGCYP3A4CYP26A1 | |
| SCHEMBL6578028 | 0.80 | RARB (0.41) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL9484975 | 0.79 | RARB (0.67) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL5737868 | 0.75 | RARB (0.52) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL7636118 | 0.75 | RARB (0.49) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL8616759 | 0.74 | RARB (0.42) | RARBRARARARGCYP3A4KMT2A | |
| SCHEMBL9007003 | 0.74 | RARB (0.66) | RARBRARARARGCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739338-A | SKIN DISORDERS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS, VISION DEFECTS, VIRICIDES, IMMUNOSUPPRESSANTS | ALLERGAN (US) | 1998-04-14 | — | — | US | disclosed |