Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.72 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.72 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.72 |
| ▸ | DHODH | Q02127 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690078 | 0.87 | DHODH (0.68) | KDM4ELMNASMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL7094226 | 0.87 | DHODH (0.68) | KDM4ELMNASMN1; SMN2DHODHALDH1A1 | |
| Cinchophen SCHEMBL29376617 | 0.86 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 | |
| Cinchophen SCHEMBL25519 | 0.86 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 | |
| Cinchophen SCHEMBL7588217 | 0.86 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 | |
| SCHEMBL4017739 | 0.85 | DHODH (0.80) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL29788466 | 0.85 | DHODH (0.80) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| Cinchophen SCHEMBL4464779 | 0.85 | KDM4E (0.97) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 | |
| Cinchophen SCHEMBL10757475 | 0.85 | KDM4E (0.97) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 | |
| Cinchophen SCHEMBL4805149 | 0.85 | KDM4E (0.97) | KDM4ELMNASMN1; SMN2PDE10AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617270-A1 | ISOINDOLINONE DERIVATIVE HAVING QUINOLINE AMIDE STRUCTURE, AND USE THEREOF | Oncord Bio Inc (KR) | 2025-09-17 | — | — | EP | disclosed |
| CN-120152966-A | Isoindolinone derivative with quinolinamide structure and application thereof | 昂科德生物株式会社 | 2025-06-13 | — | — | CN | disclosed |
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | KDM4E 2788/4885LMNA 4027/4885SMN1; SMN2 3607/4885 |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | KDM4E 2301/4885LMNA 1883/4885SMN1; SMN2 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.