Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613185 | 0.90 | PDE10A (0.49) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8617709 | 0.87 | PDE10A (0.69) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8619962 | 0.87 | TACR3 (0.42) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8614027 | 0.85 | PDE10A (0.47) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8614344 | 0.84 | PDE10A (0.52) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8617941 | 0.84 | PDE10A (0.64) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8619729 | 0.84 | CA2 (0.43) | MEN1KMT2AALDH1A1HPGDTACR3 | |
| SCHEMBL8617942 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDDHODH | |
| SCHEMBL8616298 | 0.83 | PDE10A (0.52) | PDE10AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8616466 | 0.83 | PDE10A (0.47) | PDE10AMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |