Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611371 | 0.90 | PPARA (0.39) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL8611130 | 0.87 | PPARA (0.41) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL8884805 | 0.85 | — | — | |
| SCHEMBL8611172 | 0.83 | CYSLTR2 (0.38) | PPARATSHRLTB4R | |
| SCHEMBL10383779 | 0.77 | CA2 (0.35) | TSHR | |
| SCHEMBL11091339 | 0.77 | PPARA (0.56) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL8612087 | 0.75 | PPARA (0.40) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL8611361 | 0.73 | PPARA (0.40) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL8613208 | 0.72 | CYSLTR2 (0.38) | PPARATSHRLTB4R | |
| SCHEMBL8612072 | 0.71 | PPARA (0.40) | PPARATTRCYP1A2CYP2C8CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718295-B1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN SPA (IT) | 1998-04-22 | — | — | EP | disclosed |
| US-5608084-A | AND VASCULAR PATHOLOGIES; MULTISTEP PREPARATION BY REACTING A HYDROQUINONE WITH ALKYL VINYL KETONE, ESTERIFYING HYDROXY 3,4-DIHYDRO-2H-1-BENZOPYRAN, DEMETHYLATING ETHER, REACTING WITH ALKYL 5-BROMOPENTANOATE, HYDROLYZING, TWO MORE STEPS | ALFA WASSERMANN S.P.A. (IT) | 1997-03-04 | — | — | US | disclosed |
| EP-0718295-A1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN S.p.A. (IT) | 1996-06-26 | — | — | EP | disclosed |