Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611172 | 0.89 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1LTB4RLTB4R2THRA | |
| SCHEMBL8611730 | 0.85 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1LTB4RLTB4R2THRA | |
| SCHEMBL11704397 | 0.83 | IAPP (0.33) | — | |
| SCHEMBL8610924 | 0.74 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1LTB4RLTB4R2THRA | |
| SCHEMBL8614957 | 0.72 | PPARA (0.41) | LTB4RPPARATSHR | |
| SCHEMBL8610989 | 0.69 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1LTB4RLTB4R2THRA | |
| SCHEMBL10383779 | 0.69 | CA2 (0.35) | THRBALDH1A1TSHRIMPDH1 | |
| SCHEMBL10474808 | 0.69 | IMPDH2 (0.40) | IMPDH1 | |
| SCHEMBL8612091 | 0.68 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1LTB4RLTB4R2THRA | |
| SCHEMBL11705121 | 0.66 | NPC1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718295-B1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN SPA (IT) | 1998-04-22 | — | — | EP | disclosed |
| US-5608084-A | AND VASCULAR PATHOLOGIES; MULTISTEP PREPARATION BY REACTING A HYDROQUINONE WITH ALKYL VINYL KETONE, ESTERIFYING HYDROXY 3,4-DIHYDRO-2H-1-BENZOPYRAN, DEMETHYLATING ETHER, REACTING WITH ALKYL 5-BROMOPENTANOATE, HYDROLYZING, TWO MORE STEPS | ALFA WASSERMANN S.P.A. (IT) | 1997-03-04 | — | — | US | disclosed |
| EP-0718295-A1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN S.p.A. (IT) | 1996-06-26 | — | — | EP | disclosed |