Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | HTR6 | P50406 | 7/20 | 0.63 |
| ▸ | HTR1D | P28221 | 6/20 | 0.59 |
| ▸ | GABRP | O00591 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.51 |
| ▸ | GABRE | P78334 | 3/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808971 | 0.87 | HTR1B (0.70) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8617260 | 0.87 | HTR1B (0.70) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8879855 | 0.86 | HTR1B (0.72) | HTR1BHTR1AHTR6HTR1DGABRP | |
| SCHEMBL8932358 | 0.85 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1DGABRP | |
| SCHEMBL8932357 | 0.85 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1DGABRP | |
| SCHEMBL1388908 | 0.83 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL1388907 | 0.83 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| Hydrochloric Acid SCHEMBL8612746 | 0.82 | HTR1B (0.66) | HTR1BHTR1AHTR6HTR1D | |
| Hydrochloric Acid SCHEMBL8614368 | 0.81 | HTR1B (0.61) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8881179 | 0.81 | HTR1B (0.61) | HTR1BHTR1AHTR6HTR1DGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852049-A | Aromatic ethers derived from indoles which are useful as medicaments | PIERRE FABRE MEDICAMENT (FR) | 1998-12-22 | — | — | US | disclosed |