Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 13/20 | 0.70 |
| ▸ | HTR1A | P08908 | 9/20 | 0.70 |
| ▸ | HTR6 | P50406 | 7/20 | 0.67 |
| ▸ | HTR1D | P28221 | 11/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617260 | 1.00 | HTR1B (0.70) | HTR1BHTR1AHTR6HTR1DKDM4E | |
| SCHEMBL8879855 | 0.99 | HTR1B (0.72) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8932357 | 0.88 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8932358 | 0.88 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8615007 | 0.87 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL1388908 | 0.85 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL1388907 | 0.85 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| Hydrochloric Acid SCHEMBL8612746 | 0.85 | HTR1B (0.66) | HTR1BHTR1AHTR6HTR1D | |
| Hydrochloric Acid SCHEMBL8614368 | 0.84 | HTR1B (0.61) | HTR1BHTR1AHTR6HTR1DHTR2A | |
| SCHEMBL8881179 | 0.84 | HTR1B (0.61) | HTR1BHTR1AHTR6HTR1DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782568-A1 | AROMATIC ETHERS DERIVED FROM INDOLS SUCH AS 5HT1-LIKE LIGANDS | PIERRE FABRE MEDICAMENT (FR) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009288-A1 | AROMATIC ETHERS DERIVED FROM INDOLS SUCH AS 5HT1-LIKE LIGANDS | PIERRE FABRE MEDICAMENT (FR) | 1996-03-28 | — | — | WO | disclosed |