Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265475 | 0.78 | GAA (0.50) | POLBALDH1A1GAA | |
| SCHEMBL5638728 | 0.75 | ESR2 (0.49) | LMNAALDH1A1GAAHTT | |
| SCHEMBL8615006 | 0.74 | GAA (0.47) | POLBADORA1LMNAADORA3ADORA2A | |
| SCHEMBL5637692 | 0.73 | IKBKB (0.50) | LMNAALDH1A1 | |
| SCHEMBL3737979 | 0.72 | IKBKB (0.49) | PPARALMNA | |
| SCHEMBL22678521 | 0.70 | DRD1 (0.50) | POLBLMNAALDH1A1GAAHTT | |
| SCHEMBL5638197 | 0.69 | LMNA (0.45) | POLBLMNAADORA3ADORA2AALDH1A1 | |
| SCHEMBL30638248 | 0.68 | ELANE (0.30) | — | |
| SCHEMBL2515825 | 0.64 | — | — | |
| SCHEMBL12681531 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731335-A | NERVOUS SYSTEM DISORDERS; STROKE; ANTIISCHEMIC AGENTS; COGNITION ACTIVATORS | ASTRA AKTIEBOLAG (SE) | 1998-03-24 | — | — | US | disclosed |