Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615008 | 0.74 | POLB (0.38) | GAAALDH1A1LMNAPOLBADORA2A | |
| SCHEMBL8612787 | 0.71 | HSD17B10 (0.46) | GAAALDH1A1LMNAPOLBADORA2A | |
| SCHEMBL2789941 | 0.69 | GAA (0.73) | GAAKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL31301354 | 0.68 | GAA (0.58) | GAAKDM4EALDH1A1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL11623044 | 0.68 | GAA (0.71) | GAAKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL20646882 | 0.67 | GAA (0.69) | GAAKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL3436261 | 0.67 | ALDH1A1 (0.50) | ALDH1A1POLBPLAU | |
| SCHEMBL17373915 | 0.66 | GAA (0.48) | GAAKDM4EALDH1A1LMNA | |
| SCHEMBL10049085 | 0.66 | SMN1; SMN2 (0.65) | GAAKDM4EALDH1A1POLB | |
| SCHEMBL2775125 | 0.66 | GAA (0.68) | GAAKDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731335-A | NERVOUS SYSTEM DISORDERS; STROKE; ANTIISCHEMIC AGENTS; COGNITION ACTIVATORS | ASTRA AKTIEBOLAG (SE) | 1998-03-24 | — | — | US | disclosed |