Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615598 | 0.89 | GCK (0.40) | IGF1RMAP2K1 | |
| SCHEMBL8618439 | 0.84 | IGF1R (0.62) | IGF1RMAP2K1 | |
| Hydrochloric Acid SCHEMBL8620309 | 0.83 | IGF1R (0.61) | IGF1RMAP2K1 | |
| SCHEMBL8308341 | 0.79 | IGF1R (0.50) | IGF1RMAP2K1 | |
| SCHEMBL10395308 | 0.74 | IGF1R (0.53) | IGF1RMAP2K1 | |
| SCHEMBL23434 | 0.73 | IGF1R (0.46) | IGF1RMAP2K1 | |
| SCHEMBL8615673 | 0.72 | BRAF (0.41) | IGF1RMAP2K1 | |
| SCHEMBL5254528 | 0.69 | IGF1R (0.75) | IGF1RMAP2K1 | |
| SCHEMBL4453743 | 0.69 | IGF1R (0.75) | IGF1RMAP2K1 | |
| SCHEMBL23678 | 0.69 | IGF1R (0.44) | IGF1RMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821246-A | USEFUL AS TYROSINE KINASE INHIBITORS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | ZENECA LIMITED (GB) | 1998-10-13 | — | — | US | disclosed |