Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 5/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615031 | 0.84 | FEN1 (0.44) | FEN1ALOX5APPTGER1KDM1ALRRK2 | |
| SCHEMBL8616563 | 0.84 | FEN1 (0.56) | FEN1ALOX5APPLAUPTGER1KDM1A | |
| SCHEMBL8616567 | 0.84 | ALOX5AP (0.43) | FEN1ALOX5APPLAUPTGER1KDM1A | |
| SCHEMBL8615418 | 0.79 | FEN1 (0.50) | FEN1ALOX5APKDM1AMRGPRX4 | |
| SCHEMBL8614892 | 0.78 | FEN1 (0.43) | FEN1ALOX5APPLAUPTGER1KDM1A | |
| SCHEMBL8613864 | 0.78 | MEN1 (0.46) | FEN1ALOX5APKMT2AMEN1 | |
| SCHEMBL8616633 | 0.78 | MRGPRX4 (0.48) | FEN1ALOX5APPLAUPTGER1SLC6A4 | |
| SCHEMBL23263860 | 0.77 | PTGER1 (0.44) | PLAUPTGER1LRRK2KMT2AMEN1 | |
| SCHEMBL8612501 | 0.76 | FEN1 (0.42) | FEN1ALOX5APPLAUPTGER1KDM1A | |
| SCHEMBL8612215 | 0.76 | PTGER1 (0.42) | FEN1ALOX5APPTGER1KDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |