SCHEMBL8616563

SCHEMBL8616563

Fc1c(OCc2ccccc2)ccc(-c2cnc(Cl)cn2)c1F

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 12/20 0.56
ALOX5AP P20292 10/20 0.56
KDM1A O60341 2/20 0.40
PLAU P00749 1/20 0.39
IDO1 P14902 1/20 0.36
MRGPRX4 Q96LA9 2/20 0.36
PTGER1 P34995 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615439 0.84 FEN1 (0.50) FEN1ALOX5APKDM1APLAUMRGPRX4
SCHEMBL8615418 0.84 FEN1 (0.50) FEN1ALOX5APKDM1AIDO1MRGPRX4
SCHEMBL8612501 0.82 FEN1 (0.42) FEN1ALOX5APKDM1APLAUIDO1
SCHEMBL8615031 0.79 FEN1 (0.44) FEN1ALOX5APKDM1APTGER1
SCHEMBL8616567 0.78 ALOX5AP (0.43) FEN1ALOX5APKDM1APLAUMRGPRX4
SCHEMBL8614892 0.78 FEN1 (0.43) FEN1ALOX5APKDM1APLAUIDO1
SCHEMBL8611382 0.78 ALOX5AP (0.47) FEN1ALOX5APKDM1APLAUMRGPRX4
SCHEMBL8614719 0.78 FEN1 (0.49) FEN1ALOX5AP
SCHEMBL21835671 0.78 FEN1 (0.44) FEN1ALOX5APKDM1APLAUMRGPRX4
SCHEMBL21835658 0.78 FEN1 (0.44) FEN1ALOX5APKDM1APLAUMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665836-B1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AG (DE) 1998-04-29 EP disclosed
EP-0665836-A1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-09 EP disclosed
WO-1994010152-A1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-11 WO disclosed