Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612501 | 0.86 | FEN1 (0.42) | FEN1ALOX5APCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8618508 | 0.86 | CYP19A1 (0.40) | FEN1ALOX5APCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8613871 | 0.82 | CYP11B1 (0.41) | FEN1CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL8616567 | 0.81 | ALOX5AP (0.43) | FEN1ALOX5APKDM1AMRGPRX4PLAU | |
| SCHEMBL24896625 | 0.80 | AKT1 (0.42) | FEN1CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL2111464 | 0.79 | PTGER1 (0.55) | PTGER1 | |
| SCHEMBL8614926 | 0.79 | C5AR1 (0.54) | MRGPRX4PTGER1MAPTMAPK1TDP1 | |
| SCHEMBL8615439 | 0.78 | FEN1 (0.50) | FEN1ALOX5APKDM1AMRGPRX4PLAU | |
| SCHEMBL8616563 | 0.78 | FEN1 (0.56) | FEN1ALOX5APKDM1AIDO1MRGPRX4 | |
| SCHEMBL8612828 | 0.78 | C5AR1 (0.53) | MRGPRX4PTGER1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |