Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | XDH | P47989 | 4/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793991 | 0.88 | XDH (0.53) | MRGPRX4XDHERN1PTGER1PRMT5 | |
| SCHEMBL8611753 | 0.86 | XDH (0.49) | MRGPRX4XDHERN1PTGER1PRMT5 | |
| SCHEMBL8616633 | 0.84 | MRGPRX4 (0.48) | MRGPRX4ERN1PLAUPTGER1PRMT5 | |
| SCHEMBL8615551 | 0.82 | ERN1 (0.49) | MRGPRX4XDHERN1PLAUPTGER1 | |
| SCHEMBL8613062 | 0.81 | ERN1 (0.48) | MRGPRX4ERN1PLAUPTGER1PRMT5 | |
| SCHEMBL8611382 | 0.79 | ALOX5AP (0.47) | MRGPRX4ERN1PLAUPTGER1PRMT5 | |
| SCHEMBL24363273 | 0.78 | ERN1 (0.50) | MRGPRX4XDHERN1PRMT5CTSA | |
| SCHEMBL8612030 | 0.77 | RAB9A (0.58) | PRMT5 | |
| SCHEMBL8616567 | 0.77 | ALOX5AP (0.43) | MRGPRX4PLAUPTGER1KDM1AFEN1 | |
| SCHEMBL8616560 | 0.77 | ERN1 (0.49) | MRGPRX4XDHERN1PTGER1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |