Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612536 | 0.87 | MAPT (0.46) | S1PR1S1PR3MAPTNPSR1MAPK1 | |
| SCHEMBL8612083 | 0.86 | S1PR1 (0.48) | S1PR1S1PR3MAPTNPSR1MAPK1 | |
| SCHEMBL8614719 | 0.82 | FEN1 (0.49) | MAPTNPSR1MAPK1KDM4EHSP90AA1 | |
| SCHEMBL8618126 | 0.82 | MAOB (0.47) | S1PR1S1PR3MAPTNPSR1MAPK1 | |
| SCHEMBL17443554 | 0.81 | GSTP1 (0.56) | S1PR1S1PR3MAPTNPSR1MAPK1 | |
| SCHEMBL8614184 | 0.81 | PRMT5 (0.54) | MAPTGSTP1HDAC6PRMT5MAOA | |
| SCHEMBL8616956 | 0.79 | FFAR1 (0.48) | S1PR1S1PR3GSTP1TOP1MAOB | |
| SCHEMBL8615058 | 0.79 | TOP1 (0.46) | MAPTNPSR1MAPK1KDM4EHSP90AA1 | |
| SCHEMBL8616016 | 0.79 | GSTP1 (0.54) | S1PR1S1PR3MAPTNPSR1MAPK1 | |
| SCHEMBL8612221 | 0.79 | MAOB (0.50) | TOP1ALOX5MAOAMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |