Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007210 | 0.86 | PLA2G1B (0.53) | PLA2G1BRXRARXRBRXRGPTGER1 | |
| SCHEMBL8615510 | 0.78 | PLA2G1B (0.50) | PLA2G1BPLA2G2APLA2G2EPLA2G5 | |
| SCHEMBL7014374 | 0.73 | PLA2G1B (0.57) | PLA2G1BPLA2G2APLA2G2EPLA2G5 | |
| SCHEMBL7013388 | 0.72 | PLA2G1B (0.48) | PLA2G1BPTGER1PLA2G2A | |
| SCHEMBL8318865 | 0.72 | PLA2G1B (0.48) | PLA2G1BRXRARXRBRXRGPTGER1 | |
| SCHEMBL7012444 | 0.72 | PLA2G1B (0.46) | PLA2G1BPTGER1PLA2G2APLA2G2EPLA2G5 | |
| SCHEMBL7012614 | 0.72 | PLA2G1B (0.48) | PLA2G1BPLA2G2APLA2G2EPLA2G5 | |
| SCHEMBL7013840 | 0.70 | PLA2G1B (0.47) | PLA2G1BRXRARXRBRXRGPTGER1 | |
| SCHEMBL9081030 | 0.66 | PLA2G1B (0.50) | PLA2G1BPTGER1PLA2G2ACYP2C9SMN1; SMN2 | |
| SCHEMBL4403623 | 0.66 | FOLH1 (0.51) | PTGER1MCL1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998047507-A1 | METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |