Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493489 | 0.87 | CYP1A2 (0.43) | CYP1A2CYSLTR1CYSLTR2MAPK1GPBAR1 | |
| SCHEMBL28486487 | 0.87 | CYP1A2 (0.43) | CYP1A2CYSLTR1CYSLTR2MAPK1GPBAR1 | |
| SCHEMBL31570744 | 0.84 | CYSLTR2 (0.51) | CYP1A2CYSLTR1CYSLTR2GPBAR1LMNA | |
| SCHEMBL31570746 | 0.84 | CYSLTR2 (0.51) | CYP1A2CYSLTR1CYSLTR2GPBAR1LMNA | |
| SCHEMBL28485493 | 0.84 | ALDH1A1 (0.49) | CYP1A2CYSLTR1CYSLTR2MAPK1GPBAR1 | |
| SCHEMBL22964605 | 0.82 | CYSLTR2 (0.50) | CYP1A2CYSLTR1CYSLTR2GPBAR1LMNA | |
| SCHEMBL28483931 | 0.81 | ALDH1A1 (0.49) | CYP1A2MAPK1ALDH1A1MEN1RECQL | |
| SCHEMBL29153439 | 0.80 | PNMT (0.56) | CYP1A2CYSLTR1CYSLTR2MAPK1GPBAR1 | |
| SCHEMBL19407459 | 0.79 | GRIN2D (0.53) | CYP1A2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4847350 | 0.79 | CYSLTR2 (0.47) | CYP1A2CYSLTR1CYSLTR2GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978480-A | Through C (sp)3) Green synthesis method for synthesizing quinoline derivative by synthesizing H bond functional group | 东南大学成贤学院 | 2024-11-19 | — | — | CN | disclosed |
| CN-109824585-B | Method for preparing 1-aryl-2-quinolyl ethanol compound under catalysis of acidic ionic liquid | 马鞍山市泰博化工科技有限公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-0606380-B1 | 2-SUBSTITUTED QUINOLINES FOR TREATING LEISHMANIOSES | ORSTOM (FR) | 1998-11-25 | — | — | EP | disclosed |
| US-5541196-A | ANTIPROTOZOA AGENTS | INSTITUT FRANCAIS DE RECHERCHE SCIENTIFIQUE POUR LE DEVELOPPMENT EN COOPERATION (ORSTOM) (FR) | 1996-07-30 | — | — | US | disclosed |
| EP-0606380-A1 | 2-SUBSTITUTED QUINOLINES FOR TREATING LEISHMANIOSES | INSTITUT FRANCAIS DE RECHERCHE SCIENTIFIQUE POUR LE DEVELOPPEMENT EN COOPERATION (ORSTOM) (FR) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993007125-A1 | 2-SUBSTITUTED QUINOLINES FOR TREATING LEISHMANIOSES | INSTITUT FRANÇAIS DE RECHERCHE SCIENTIFIQUE POUR LE DEVELOPPEMENT EN COOPERATION (ORSTOM) (FR) | 1993-04-15 | — | — | WO | disclosed |