Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.51 |
| ▸ | DRD5 | P21918 | 3/20 | 0.51 |
| ▸ | HRH2 | P25021 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760958 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| SCHEMBL8616378 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| Hydrochloric Acid SCHEMBL7543578 | 0.99 | MEN1 (0.52) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| Hydrochloric Acid SCHEMBL8867248 | 0.99 | MEN1 (0.52) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| SCHEMBL8677737 | 0.97 | SCN5A (0.51) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| SCHEMBL7751410 | 0.97 | SLC6A3 (0.47) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| Hydrochloric Acid SCHEMBL7543312 | 0.96 | MEN1 (0.48) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| SCHEMBL7754343 | 0.95 | CYP3A4 (0.53) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| Hydrochloric Acid SCHEMBL7542285 | 0.94 | MEN1 (0.54) | CYP3A4CYP2D6FAAHTSHRALOX12 | |
| SCHEMBL7755959 | 0.93 | SLC6A3 (0.50) | SLC6A3DRD3DRD4DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |