SCHEMBL8615795

SCHEMBL8615795

CCOc1ccc2ocnc2c1.Cc1cc(C)c2ncoc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 2/20 0.37
RAB9A P51151 2/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP3 P42574 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SENP8 Q96LD8 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 1/20 0.35
CYP1A2 P05177 2/20 0.33
DYRK1A Q13627 1/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032549 0.85 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL9440539 0.79 CYP11B1 (0.43) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL927066 0.77 PARP1 (0.35) ALDH1A1KDM4EHPGDMAPTTSHR
SCHEMBL9787502 0.73 ELANE (0.43) MAPTKMT2AMEN1
SCHEMBL8959116 0.73 CYP2D6 (0.45) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL8975216 0.73 KMT2A (0.47) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL28309111 0.70 ACHE (0.50) KMT2AMEN1CTNNB1WNT3A
SCHEMBL31286079 0.70 MEN1 (0.45) ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1
SCHEMBL22276899 0.70 MEN1 (0.45) ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1
SCHEMBL926786 0.69 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467370-B1 Sensitizing dyes for photographic materials EASTMAN KODAK CO (US) 1998-05-13 EP disclosed
US-5597687-A SILVER HALIDE EMULSIONS ON SUPPORTS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1997-01-28 US disclosed
EP-0472004-B1 Sensitizing dye combination for photographic materials EASTMAN KODAK CO (US) 1996-06-26 EP disclosed
EP-0420011-B1 Infrared-sensitive photographic element containing at least two photosensitive layers EASTMAN KODAK CO (US) 1995-12-13 EP disclosed
EP-0432473-B1 Photographic element EASTMAN KODAK CO (US) 1995-10-18 EP disclosed
EP-0435136-B1 Photographic sensitizing dyes EASTMAN KODAK CO (US) 1995-09-06 EP disclosed
EP-0451816-B1 Sensitizing dye for photographic materials EASTMAN KODAK CO (US) 1995-07-05 EP disclosed
US-5135845-A Fluorine-substitued cyanine dyes; antisoilants; black and white and color photography EASTMAN KODAK COMPANY (US) 1992-08-04 US disclosed
US-5108882-A INFRARED-SENSITIVE PHOTOGRAPHIC ELEMENT CONTAINING AT LEAST TWO PHOTOSENSITIVE LAYERS EASTMAN KODAK COMPANY (US) 1992-04-28 US disclosed
EP-0472004-A1 Sensitizing dye combination for photographic materials EASTMAN KODAK COMPANY (US) 1992-02-26 EP disclosed
US-5091298-A Low-staining cyanine dyes containing one or two sulfoalkylenecarbonyliminoalkylene groups attached to a ring nitrogen EASTMAN KODAK COMPANY (US) 1992-02-25 US disclosed
EP-0467370-A1 Sensitizing dyes for photographic materials EASTMAN KODAK COMPANY (US) 1992-01-22 EP disclosed
US-5077191-A Thiazoline or imidazoline dyes for silver halide emulsions EASTMAN KODAK COMPANY (US) 1991-12-31 US disclosed
EP-0451816-A1 Sensitizing dye for photographic materials EASTMAN KODAK COMPANY (US) 1991-10-16 EP disclosed
EP-0435136-A1 Photographic sensitizing dyes EASTMAN KODAK COMPANY (US) 1991-07-03 EP disclosed
EP-0432473-A1 Photographic element EASTMAN KODAK COMPANY (US) 1991-06-19 EP disclosed
US-5013642-A Sensitivity to infrared radiation EASTMAN KODAK COMPANY (US) 1991-05-07 US disclosed
EP-0420011-A1 Infrared-sensitive photographic element containing at least two photosensitive layers EASTMAN KODAK COMPANY (US) 1991-04-03 EP disclosed
US-4975362-A Silver halide emulsion and a cyanine dye for use with diode lasers EASTMAN KODAK COMPANY (US) 1990-12-04 US disclosed