Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL4557546 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL2391146 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL2456472 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL6704394 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL4304807 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL3630221 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL7695098 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL5133360 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL1395290 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 | |
| Methylene Chloride SCHEMBL5091282 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835817-B | Esters of steroid amides and bis (2-chloroethyl) aminophenoxypropionic acid derivatives | 格林尼卡股份公司 | 2020-04-21 | — | — | CN | disclosed |
| US-10208083-B2 | Esters of steroidal lactam and bis(2-chloroethyl) aminophenoxy propanoic acid derivatives | GALENICA S.A. (GR) | 2019-02-19 | — | — | US | disclosed |
| EP-3186268-B1 | ESTERS OF STEROIDAL LACTAM AND BIS(2-CHLOROETHYL) AMINOPHENOXY PROPANOIC ACID DERIVATIVES | GALENICA S A (GR) | 2018-11-28 | — | — | EP | disclosed |
| US-20180194800-A1 | ESTERS OF STEROIDAL LACTAM AND BIS(2-CHLOROETHYL) AMINOPHENOXY PROPANOIC ACID DERIVATIVES | GALENICA S.A. (GR) | 2018-07-12 | — | — | US | disclosed |
| EP-2491022-B1 | DIAZEPAN DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2014-12-31 | — | — | EP | disclosed |
| US-8901315-B2 | Thienopyrazole derivative having PDE7 inhibitory activity | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20140073799-A1 | THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2307387-B1 | NOVEL HETEROCYCLYL COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISEASE | HOFFMANN LA ROCHE (CH) | 2013-11-20 | — | — | EP | disclosed |
| US-8445674-B2 | Heterocyclyl compounds | Hoffmann-La Roche Inc (US) | 2013-05-21 | — | — | US | disclosed |
| EP-1775298-B1 | THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY | DAIICHI SANKYO CO LTD (JP) | 2013-03-20 | — | — | EP | disclosed |
| WO-2007110214-A1 | 12-AZA-EP0THIL0NES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIPROLIFERATIVE AGENTS | ETH Zürich (CH) | 2007-10-04 | — | — | WO | disclosed |
| EP-1775298-A1 | THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY | Daiichi Asubio Pharma Co., Ltd. (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| US-6517739-B2 | Ferulic acid, 4-hydroxy-4'-cyanobiphenyl ester where the hydroxy group on the ferulic acid is derivatized with polyethylene glycol, a crown ether group, or an azacrown ether group | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 2003-02-11 | — | — | US | disclosed |
| US-20020137962-A1 | Ferulic acid derivative, and liquid crystal material, cation detecting element, anion detecting element, ion conducting material and electrolyte, each using the ferulic acid derivative | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2002-09-26 | — | — | US | disclosed |
| US-6441217-B2 | DETECTOR | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 2002-08-27 | — | — | US | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |
| US-20010021423-A1 | Ferulic acid derivative, and liquid crystal material, cation detecting element , anion detecting element, ion conducting material and electrolyte, each using the ferulic acid derivative | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2001-09-13 | — | — | US | disclosed |
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0196271-A2 | Estradiol and/or estriol glycolic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073799-A1 | THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY | PDE7A, PDE7B, PDE3B | ALDH1A1 2864/4885TDP1 811/4885TRPA1 1739/4885 |
| US-20180194800-A1 | ESTERS OF STEROIDAL LACTAM AND BIS(2-CHLOROETHYL) AMINOPHENOXY PROPANOIC ACID DERIVATIVES | CYP4A11, PAICS, CYP51A1 | ALDH1A1 1828/4885TDP1 4263/4885TRPA1 4794/4885 |
| US-20020137962-A1 | Ferulic acid derivative, and liquid crystal material, cation detecting element, anion detecting element, ion conducting material and electrolyte, each using the ferulic acid derivative | FER, FGF23, SLC22A16 | ALDH1A1 607/4885TDP1 4675/4885TRPA1 997/4885 |
| US-20010021423-A1 | Ferulic acid derivative, and liquid crystal material, cation detecting element , anion detecting element, ion conducting material and electrolyte, each using the ferulic acid derivative | FER, FGF23, SLC22A16 | ALDH1A1 607/4885TDP1 4675/4885TRPA1 997/4885 |
| US-10208083-B2 | Esters of steroidal lactam and bis(2-chloroethyl) aminophenoxy propanoic acid derivatives | CYP4A11, PAICS, CYP51A1 | ALDH1A1 1828/4885TDP1 4263/4885TRPA1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.