Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 14/20 | 0.50 |
| ▸ | MAOB | P27338 | 14/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591224 | 0.86 | PBRM1 (0.47) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL23051659 | 0.86 | PBRM1 (0.47) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL15689674 | 0.84 | MAOA (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL21155472 | 0.84 | MAPK1 (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL16858594 | 0.84 | MAPK1 (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL23782883 | 0.84 | MEN1 (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL15689518 | 0.84 | MEN1 (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL21772243 | 0.84 | MEN1 (0.49) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL30811403 | 0.84 | MAOA (0.53) | MEN1MAPK1KMT2ANPSR1MAOA | |
| SCHEMBL29181736 | 0.84 | MAOA (0.53) | MEN1MAPK1KMT2ANPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753655-A | PROGESTINS OR ANTIPROGESTINS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |