SCHEMBL8616006

SCHEMBL8616006

COC(=O)C(=S)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
AKR1B1 P15121 1/20 0.48
ALDH1A1 P00352 5/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 1/20 0.47
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 1/20 0.46
NPC1 O15118 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11067848 0.87 ALDH1A1 (0.44) CES2CES1AKR1B1ALDH1A1LMNA
SCHEMBL7329972 0.81 ALDH1A1 (0.51) CES2CES1AKR1B1ALDH1A1MEN1
SCHEMBL667371 0.81 ALDH1A1 (0.53) ALDH1A1LMNAPOLBKDM4EHDAC8
Methyl Phenylpyruvate SCHEMBL237446 0.80 CES2 (0.64) CES2CES1AKR1B1ALDH1A1LMNA
Methyl Phenylpyruvate SCHEMBL27849227 0.78 CES2 (0.61) CES2CES1AKR1B1ALDH1A1LMNA
SCHEMBL6723396 0.77 CES1 (0.58) CES2CES1AKR1B1ALDH1A1LMNA
SCHEMBL28118587 0.77 CES2 (0.48) CES2CES1AKR1B1ALDH1A1LMNA
SCHEMBL1666500 0.77 CES2 (0.48) CES2CES1AKR1B1ALDH1A1LMNA
SCHEMBL28727350 0.76 HPGD (0.60) CES2CES1AKR1B1ALDH1A1LMNA
Methyl Phenylpyruvate SCHEMBL7622542 0.76 CES2 (0.57) CES2CES1AKR1B1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021042814-A1 ALKYL THIOETHER ETHYL HYDROXIMIC ACID BENEFICIATION AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF 中南大学 2021-03-11 WO disclosed
US-5744426-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0763025-A1 SUBSTITUTED 3-PHENYLPYRAZOLES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-03-19 EP disclosed