Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004588 | 0.88 | TSHR (0.59) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL914622 | 0.88 | ALDH1A1 (0.51) | TSHRALDH1A1HSD17B10KMT2ALMNA | |
| SCHEMBL8671766 | 0.86 | MAPT (0.42) | TSHRALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL31733655 | 0.84 | MAPT (0.51) | TSHRALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL915187 | 0.84 | FOLH1 (0.45) | TSHRALDH1A1HSD17B10NPSR1HTT | |
| SCHEMBL7219619 | 0.84 | TSHR (0.62) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31733476 | 0.84 | TSHR (0.41) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7765311 | 0.83 | TSHR (0.56) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9449012 | 0.81 | HTT (0.41) | TSHRALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL578128 | 0.80 | TSHR (0.77) | TSHRALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080117-C | Treatment of tumors with compounds having RXR retinoid receptor agonist activity | ALLERGAN INC (US) | 2002-03-06 | — | — | CN | disclosed |
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |
| CN-1122105-A | Treatment of tumors with compounds having RXR retinoid receptor agonist activity | ALLERGAN INC (US) | 1996-05-08 | — | — | CN | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |