Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623490 | 0.86 | KDM4E (0.39) | EPHX2MAPTKDM4EMEN1GAA | |
| SCHEMBL8618469 | 0.73 | EPHX2 (0.47) | EPHX2MAPTKDM4EMEN1GAA | |
| Diphenylamine SCHEMBL29173772 | 0.69 | HSD17B10 (0.67) | EPHX2MAPTKDM4EMEN1GAA | |
| SCHEMBL809569 | 0.69 | MAPT (0.47) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL2431454 | 0.69 | CA12 (0.52) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL29813222 | 0.69 | MAPT (0.47) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL28391601 | 0.67 | L3MBTL1 (0.62) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL444976 | 0.66 | MAPT (0.70) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL29734978 | 0.66 | KCNH3 (0.54) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL6687184 | 0.66 | KCNH3 (0.54) | MAPTKDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |