SCHEMBL8616207

SCHEMBL8616207

CCCCOC(=O)/C=C/C(=O)OOC(C)(C)C

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.69
HCAR2 Q8TDS4 5/20 0.61
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TSHR P16473 2/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 1/20 0.42
APP P05067 5/20 0.42
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892638 0.90 ATM (0.65) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8892632 0.90 ATM (0.65) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9245719 0.85 HCAR2 (0.58) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9245726 0.85 HCAR2 (0.58) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL27804667 0.84 HCAR2 (0.69) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244457 0.84 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244681 0.84 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244689 0.84 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9243244 0.84 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244445 0.84 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5644004-A Multi-component ethylenically unsaturated peroxyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-07-01 US claimed
EP-0667339-B1 Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses ATOCHEM NORTH AMERICA ELF (US) 1998-05-06 EP disclosed
US-5644004-A Multi-component ethylenically unsaturated peroxyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-07-01 US disclosed
US-5494988-A FREE RADICAL INITIATORS AS MONOMERS; CROSSLINKING UNSATURATED POLYESTERS; ADDITION, GRAFT AND BLOCK POLYMERIZATION; COMPATIBILIZING BLENDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-02-27 US disclosed
US-5489699-A USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND ELFATOCHEM NORTH AMERICA, INC. (US) 1996-02-06 US disclosed
US-5475072-A Curing; crosslinking; modifiying; grafting; compatibilizing ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-12 US disclosed
EP-0667339-A1 Novel unsaturated peroxides, polymeric derived therefrom and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-08-16 EP disclosed
US-5420173-A Curing unsaturated polyesters and peroxyester compositions ARKEMA INC. 1995-05-30 US disclosed