Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.54 |
| ▸ | RXRB | P28702 | 12/20 | 0.54 |
| ▸ | RXRG | P48443 | 10/20 | 0.54 |
| ▸ | RARB | P10826 | 8/20 | 0.54 |
| ▸ | RARG | P13631 | 8/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.51 |
| ▸ | RARA | P10276 | 6/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720638 | 0.81 | RXRA (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL28949691 | 0.72 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7723487 | 0.71 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8101815 | 0.68 | RXRA (0.50) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7759680 | 0.68 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17911573 | 0.68 | CYP26A1 (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5681933 | 0.68 | RARB (0.82) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7812840 | 0.66 | RXRA (0.34) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL24259972 | 0.66 | CYP26A1 (0.76) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17911596 | 0.66 | CYP26A1 (0.81) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679630-B1 | Bicyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses | CIRD GALDERMA (FR) | 1998-05-06 | — | — | EP | claimed |