Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.34 |
| ▸ | RXRB | P28702 | 5/20 | 0.33 |
| ▸ | RXRG | P48443 | 5/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424636 | 0.82 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7813388 | 0.77 | — | — | |
| SCHEMBL7816655 | 0.74 | RARA (0.35) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7812219 | 0.73 | RXRA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7771303 | 0.71 | RXRA (0.45) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7813057 | 0.71 | PPARG (0.31) | RXRARXRBRXRGNR4A2 | |
| SCHEMBL7813043 | 0.71 | RARA (0.34) | RXRARXRGRARBRARGNR4A2 | |
| SCHEMBL7806225 | 0.71 | RARA (0.34) | RXRARXRGRARBRARGNR4A2 | |
| SCHEMBL7808934 | 0.71 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8423718 | 0.70 | CYP3A4 (0.38) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816352-B1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CT INTERNAT DE (FR) | 2001-02-21 | — | — | EP | claimed |