Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614759 | 0.95 | GSTP1 (0.49) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8613875 | 0.95 | GSTP1 (0.48) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8618479 | 0.95 | GSTP1 (0.48) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8616555 | 0.92 | ALOX5 (0.44) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8616187 | 0.92 | GSTP1 (0.55) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8616652 | 0.91 | GSTP1 (0.50) | GSTP1MAOBTOP1ALOX5MAOA | |
| SCHEMBL8616319 | 0.89 | GSTP1 (0.53) | GSTP1MAOBALOX5MAOALCK | |
| SCHEMBL8614981 | 0.89 | GSTP1 (0.53) | GSTP1MAOBALOX5MAOALCK | |
| SCHEMBL29597315 | 0.89 | MAOB (0.57) | MAOBTOP1ALOX5MAOACTSV | |
| SCHEMBL320455 | 0.89 | MAOB (0.57) | MAOBTOP1ALOX5MAOACTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |