SCHEMBL8613875

SCHEMBL8613875

Fc1cc(-c2ccc(-c3ccc(OCc4ccccc4)cc3F)cc2F)ccc1Br

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 2/20 0.48
S1PR1 P21453 1/20 0.47
S1PR3 Q99500 1/20 0.47
MAOB P27338 6/20 0.47
TOP1 P11387 1/20 0.46
ALOX5 P09917 1/20 0.45
MAOA P21397 5/20 0.45
CTSV O60911 1/20 0.43
CTSL P07711 1/20 0.43
FFAR1 O14842 3/20 0.43
PPARD Q03181 1/20 0.43
PDK2 Q15119 1/20 0.42
LCK P06239 1/20 0.42
FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618479 1.00 GSTP1 (0.48) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8614759 0.95 GSTP1 (0.49) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8616533 0.95 GSTP1 (0.48) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8616652 0.93 GSTP1 (0.50) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8616555 0.92 ALOX5 (0.44) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8616187 0.92 GSTP1 (0.55) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8612914 0.90 ALOX5 (0.44) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL8616016 0.89 GSTP1 (0.54) GSTP1S1PR1S1PR3MAOBTOP1
SCHEMBL29597315 0.89 MAOB (0.57) MAOBTOP1ALOX5MAOACTSV
SCHEMBL320455 0.89 MAOB (0.57) MAOBTOP1ALOX5MAOACTSV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665836-B1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AG (DE) 1998-04-29 EP disclosed
WO-1994010152-A1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-11 WO disclosed