Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.49 |
| ▸ | ANPEP | P15144 | 5/20 | 0.49 |
| ▸ | BACE1 | P56817 | 9/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616672 | 1.00 | LNPEP (0.49) | LNPEPANPEPBACE1ACEMME | |
| SCHEMBL8615303 | 0.91 | LNPEP (0.51) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL8615323 | 0.91 | LNPEP (0.51) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL8619183 | 0.90 | LNPEP (0.58) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL8619169 | 0.90 | LNPEP (0.58) | LNPEPANPEPACEMMECPA1 | |
| Hydrochloric Acid SCHEMBL8619036 | 0.88 | LNPEP (0.54) | LNPEPANPEPACEMMECPA1 | |
| Hydrochloric Acid SCHEMBL8619053 | 0.88 | LNPEP (0.54) | LNPEPANPEPACEMMECPA1 | |
| Hydrochloric Acid SCHEMBL8614607 | 0.85 | ANPEP (0.52) | LNPEPANPEPACEMMECPA1 | |
| Hydrochloric Acid SCHEMBL8614620 | 0.85 | ANPEP (0.52) | LNPEPANPEPACEMMECPA1 | |
| Hydrochloric Acid SCHEMBL8613590 | 0.84 | CTSD (0.56) | LNPEPANPEPBACE1ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |