SCHEMBL8616893

SCHEMBL8616893

CCCCCCCCC(CCCCCC)C(=O)Nc1cc(NC(=O)C(CCCCCC)CCCCCCCC)cc(C([NH])=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 2/20 0.48
HDAC8 Q9BY41 5/20 0.45
HDAC3 O15379 3/20 0.45
HDAC6 Q9UBN7 3/20 0.45
HDAC1 Q13547 3/20 0.45
HDAC2 Q92769 2/20 0.45
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1525323 0.87 MEN1 (0.63) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL1525705 0.87 MEN1 (0.68) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL8616897 0.86 MEN1 (0.50) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL1820404 0.86 LMNA (0.48) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL15020945 0.86 MEN1 (0.61) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL1525416 0.84 LMNA (0.65) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL1525510 0.84 LMNA (0.69) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL15021080 0.83 LMNA (0.68) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL18744149 0.82 LMNA (0.44) MEN1KMT2ALMNAHDAC8HDAC3
SCHEMBL18744153 0.80 LMNA (0.44) MEN1KMT2ALMNAHDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320821-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
US-5652088-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-07-29 US disclosed
US-5126234-A Pyrazolone-based magenta coupler; low fog, high color density FUJI PHOTO FILM CO., LTD. (JP) 1992-06-30 US disclosed
US-4978606-A CONTAINING HYDROQUINONES AND SULFONAMIDOPHENOLS; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1990-12-18 US disclosed