Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618466 | 0.98 | MEN1 (0.42) | TSHRMAPK1MEN1KMT2ANOS1 | |
| SCHEMBL10918832 | 0.78 | — | — | |
| SCHEMBL2678664 | 0.76 | TSHR (0.50) | TSHRMAPK1MEN1KMT2ANOS1 | |
| SCHEMBL6412595 | 0.74 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2ANOS1 | |
| SCHEMBL4094073 | 0.74 | — | — | |
| SCHEMBL10298186 | 0.72 | TSHR (0.50) | TSHRMAPK1MEN1KMT2ANOS1 | |
| Di(Hydroxyethyl)Ether SCHEMBL2271102 | 0.69 | TSHR (0.71) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL23743149 | 0.69 | — | — | |
| SCHEMBL11402999 | 0.69 | — | — | |
| SCHEMBL6337634 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |