Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412595 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL2730996 | 0.76 | MEN1 (0.41) | TSHRMEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL4111817 | 0.76 | MEN1 (0.41) | TSHRMEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL4094464 | 0.76 | NOS1 (0.37) | MEN1KMT2ACYP1A2ALOX15NFKB1 | |
| SCHEMBL6938637 | 0.76 | NOS1 (0.37) | MEN1KMT2ACYP1A2ALOX15NFKB1 | |
| SCHEMBL8616922 | 0.76 | TSHR (0.40) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10298186 | 0.75 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL1427854 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1479729 | 0.75 | MEN1 (0.40) | TSHRMEN1KMT2ACYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL17156891 | 0.75 | MEN1 (0.40) | TSHRMEN1KMT2ACYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805674-B1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORP (JP) | 2003-03-12 | — | — | EP | claimed |
| US-6348200-B1 | OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES | KAO CORPORATION (JP) | 2002-02-19 | — | — | US | claimed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | claimed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | claimed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | claimed |
| JP-11217316-A | — | — | None | — | — | JP | disclosed |
| JP-9095477-A | — | — | None | — | — | JP | disclosed |
| EP-3861971-B1 | ABSORBENT ARTICLE | KAO CORP (JP) | 2023-12-27 | — | — | EP | disclosed |
| EP-3861971-A1 | ABSORBENT ARTICLE | Kao Corporation (JP) | 2021-08-11 | — | — | EP | disclosed |
| JP-2012006840-A | COSMETIC | KAO CORP | 2012-01-12 | — | — | JP | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| EP-0904772-A1 | SKIN COLOR IMPROVER | Kao Corporation (JP) | 1999-03-31 | — | — | EP | disclosed |
| EP-0872228-A1 | COSMETOLOGICAL METHODS | Kao Corporation (JP) | 1998-10-21 | — | — | EP | disclosed |
| CN-1038248-C | Diguanide derivatives, process of preparation thereof and disinfetants containing them | OTSUKA CHEMCIAL CO LTD (JP) | 1998-05-06 | — | — | CN | disclosed |
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
| JP-H0995477-A | GUANIDINE DERIVATIVE AND ITS PRODUCTION | KAO CORP | 1997-04-08 | — | — | JP | disclosed |
| CN-1065453-A | Biguanide derivative, its manufacture method and the Herb of Common violet that contains this derivative | OTSUKA CHEMICAL CO LTD (JP) | 1992-10-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | TSHR 1694/4885MAPK1 1423/4885MEN1 261/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | TSHR 3766/4885MAPK1 944/4885MEN1 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.