Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618418 | 0.82 | FFAR1 (0.33) | FFAR1FFAR4PLAUACACB | |
| SCHEMBL16726799 | 0.79 | FFAR1 (0.32) | FFAR1FFAR4PLAUASIC3 | |
| SCHEMBL12736435 | 0.78 | CYP2A6 (0.45) | GRM5FFAR1FFAR4ASIC3TRPV3 | |
| SCHEMBL16726798 | 0.77 | FFAR1 (0.36) | FFAR1PLAUASIC3 | |
| SCHEMBL8616508 | 0.76 | LOXL2 (0.48) | FFAR1 | |
| SCHEMBL7861686 | 0.75 | ACACB (0.43) | GRM5FFAR1FFAR4PLAUACACB | |
| SCHEMBL12736440 | 0.75 | ACACB (0.43) | GRM5FFAR1FFAR4PLAUACACB | |
| SCHEMBL9508806 | 0.73 | GRM5 (0.41) | GRM5FFAR1FFAR4TRPV3ACACB | |
| SCHEMBL14228694 | 0.71 | GRM5 (0.49) | GRM5FFAR1FFAR4 | |
| SCHEMBL14525802 | 0.71 | HSD17B10 (0.47) | FFAR1FFAR4ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |